Abstract: 12-Phosphotungstics acid(PW12) supported on SiO2 were prepared by the sol-gel method. The effect of preparation conditions on the catalytic performance in synthesis of tributyl citrate (TBC) with critic acid and n-butyl alcohol was investigated and the mechanism was discussed. The results showed that 10%(mass) PW12 made by 2 g PW12，3 mL pure water and ethanol as co-solvent and activated at 110 ℃ had good activity and stability. Esterification ratio was 97.1% with high purity of the product TBC.

摘要： 以二氧化硅为载体，采用溶胶-凝胶法制备了固载磷钨酸（PW12 /SiO2）催化剂，并用于催化合成柠檬酸三丁酯（TBC）。研究了催化剂制备条件对催化性能的影响并对其机理进行了探讨。用3 mL蒸馏水溶解2 g磷钨酸（PW12），以乙醇为助溶剂制备负载量为10%的催化剂，在110 ℃活化，用于酯化反应后酯化率达97.1%，产品纯度高。重复性实验表明，PW12 /SiO2 有很好的稳定性，使用7次后酯化率略有下降，是理想的合成柠檬酸三丁酯的催化剂。