Abstract: In this paper 2, 4, 6-trimethylbenzoic acid was synthesized by carboxylation of mesitylene in carbon dioxide–AlCl3 system. To optimize reaction conditions, experimental variables including reaction temperature and molar ratio were studied. The results showed the yield was as high as 83.3% when the molar ratio of mesitylene and AlCl3 was 0.7∶1 at room temperature.

摘要： 考察了在以均三甲苯为原料、CO2和AlCl3为酰化剂经Friedel-Crafts酰基化反应、水解合成2, 4, 6-三甲基苯甲酸工艺过程中，物料配比、反应温度等反应条件对收率的影响，确定了适宜的反应条件和后处理条件。通过此合成工艺，产品的产率可达83.3%。