Abstract:

The acetalization and ketalization of various aldehydes and ketones with glycols using FeCl₃ as catalyst were studied. The effects of reaction time, mole ratio of reactants and amount of catalyst on the yield of acetals (ketals) were investigated. The results showed that FeCl₃ was an efficient catalyst for the acetalization and ketalization with high conversion and selectivity in mild conditions. The best reaction conditions were: molar ratio of aldehydes and ketones to glycol 1∶1.2，catalyst amount 2 g/mol aldehydes or ketones, reaction time 2 h. The conversion was over 95% and selectivity was over 97%.

摘要： 研究了在FeCl3催化下，乙二醇与环己酮、丁酮、丙酮、丙醛、丁醛、异丁醛、戊醛、异戊醛、正辛醛、二苯甲酮、苯甲醛等十余种醛（酮）的缩合反应。考察了反应时间、醛(酮)与醇的配比、FeCl3的用量及催化剂重复使用等因素对反应的影响，优化了反应条件。结果表明，当醛（酮）与乙二醇物质的量比为1∶1.2，催化剂用量为2 g/mol醛（酮），反应2 h，转化率可达95%以上，选择性可达97%以上。证明FeCl3对该缩合反应有较好的催化活性和选择性。