Abstract:

With the continuous progress of social economy and plentifulness of the physical life, the use of cosmetics has become more and more common. Driven by economically motivated adulteration (EMA), fake and shoddy cosmetics in the market is becoming more and more serious. But the current quality traceability is mainly carried out through information tracing, so it is very necessary to establish a high-precision, fast and convenient detection method of cosmetics quality traceability. In this study, REIMS technology was used to test authentic and commercial cosmetics samples. In addition, clustering analysis was made to analysis liquid and milky sample under positive and negative mode respectively. Then, PCA-LDA models were constructed to find suspected counterfeits. Besides, the authentic cosmetics samples were used to build a discriminant model, and the commercial samples were distinguished to ascertain the counterfeit cosmetics. Then, Progenesis QI software was used to analyze the difference of mass spectrometry information between real and fate cosmetics samples and infer the structure. then, the main quality traceability target factors were determined, which laid a foundation for the standardization of rapid detection technology of cosmetics and quantitative detection of characteristic target species in the future.

Key words: rapid evaporative ionization mass spectrometry(REIMS), cosmetics, quality traceability, identification model, rapid identification

摘要：

随着社会经济的不断进步和物质生活的丰富，化妆品的使用已经越来越普遍。在经济利益驱动下，市场上假冒伪劣化妆品的情况日益严重，但是现行质量溯源主要是通过信息溯源进行，所以建立一种高精度、快速便捷的化妆品质量溯源技术方法是十分必要的。本文采用快速蒸发电离质谱技术（REIMS）对正品化妆品及市售样品进行检测，采用Live ID软件，分别对正、负离子模式下的液状样品和乳状样品进行聚类分析，构建PCA-LDA模型，查找可疑的伪品。随后，应用正品化妆品样品构建判别模型，并对市售样品进行鉴定，确定伪造化妆品。使用Progenesis QI软件对真伪化妆品进行差异因子分析并鉴定，确定主要质量溯源靶标因子，为将来化妆品真伪快速检测技术标准化及特征靶标物种定量检测奠定基础。

关键词: 快速蒸发电离质谱技术, 化妆品, 质量溯源, 判别模型, 快速检测