Abstract: The recent progress of Sonogashira-type coupling reaction catalyzed by heterogeneous catalyst Pd/C is presented. Remarkable catalytic activity and increased reaction rate are observed in Sonogashira-type coupling reaction catalyzed by Pd/C，especially some reactions for which many homogeneous catalysts are ineffective，and the process can be carried out in copper-free，ligand-free，amine-free conditions but with water and/or by exposure to air by changing the reaction conditions. These improvements result in an expanded scope of reactants. All these advantages enable such reaction to be performed in environment-friendly conditions，making its commercialization possible.