Abstract: Ion exchange chromatography is a promising technique for boron isotopes separation. It has relatively high efficiency and low energy consumption. The latest progress for enriching 10B isotope by ion exchange chromatography is reviewed. In current research, strong-base anion exchange resin, weak-base anion exchange resin and boron-specific resin are used as column packing material. Their advantages and disadvantages are compared. Some elements affecting the single-stage separation factor are discussed.