Abstract: Existing problems for the application of methanol fuel in China are analyzed，mainly including the toxicity，compatibility with gasoline，corrosiveness，and vaporizability. The application of methanol gasoline abroad is described and the reasons for without the use of methanol gasoline. In case of China，the main problem is the lack of specifications for low percentage methanol gasoline，large-scale promotion of methanol gasoline should have real practical policy measures and scientific data，addressing issues need to be resolved from environmental protection，automobile and oil quality.