FeCl3催化合成缩醛（酮）

化工进展

FeCl3催化合成缩醛（酮）

梁学正，高珊，于心玉，刘彩华，杨建国

华东师范大学，上海市绿色化学与化工过程绿色化重点实验室

出版日期:2006-06-25 发布日期:2006-06-25

Catalytic synthesis of acetals (ketals) by FeCl3

LIANG Xuezheng，GAO Shan，YU Xinyu，LIU Caihua，YANG Jianguo

Shanghai Key Laboratory of Green Chemistry and Chemical Process , East China Normal University

Online:2006-06-25 Published:2006-06-25

摘要/Abstract

摘要： 研究了在FeCl3催化下，乙二醇与环己酮、丁酮、丙酮、丙醛、丁醛、异丁醛、戊醛、异戊醛、正辛醛、二苯甲酮、苯甲醛等十余种醛（酮）的缩合反应。考察了反应时间、醛(酮)与醇的配比、FeCl3的用量及催化剂重复使用等因素对反应的影响，优化了反应条件。结果表明，当醛（酮）与乙二醇物质的量比为1∶1.2，催化剂用量为2 g/mol醛（酮），反应2 h，转化率可达95%以上，选择性可达97%以上。证明FeCl3对该缩合反应有较好的催化活性和选择性。

Abstract:

The acetalization and ketalization of various aldehydes and ketones with glycols using FeCl₃ as catalyst were studied. The effects of reaction time, mole ratio of reactants and amount of catalyst on the yield of acetals (ketals) were investigated. The results showed that FeCl₃ was an efficient catalyst for the acetalization and ketalization with high conversion and selectivity in mild conditions. The best reaction conditions were: molar ratio of aldehydes and ketones to glycol 1∶1.2，catalyst amount 2 g/mol aldehydes or ketones, reaction time 2 h. The conversion was over 95% and selectivity was over 97%.

梁学正，高珊，于心玉，刘彩华，杨建国. FeCl3催化合成缩醛（酮） [J]. 化工进展.

LIANG Xuezheng，GAO Shan，YU Xinyu，LIU Caihua，YANG Jianguo. Catalytic synthesis of acetals (ketals) by FeCl3[J]. Chemical Industry and Engineering Progree.