Abstract:

2-Ethylhexyl p-dimethylamiobenzoate was synthesized with higher yield，lower cost and nontoxicity，which is easier realized for large-scale industrial production. Dimethylamino benzoic acid and isooctanol were used as starting materials without any solvent by using p-toluenesulfonic acid as a esterification catalyst. The reaction proceeded as much as possible to remove the produced water under highly reduced pressure，and the reaction temperature was controlled in a range between 110℃and 120℃. The reaction conditions of the esterification without solvent should be emphasized that the temperature was between 110 and 120 ℃ at a negative pressure of 0.095 MPa for 6h. The molar ratio of dimethyl-aminobenzoic acid with isooctanol was 1∶3.5. 2-Ethylhexyl p-dimethylamiobenzoate yield was higher than 90% based ondimethyl-aminobenzoic acid.