Abstract: Degradation of reactive red dye 3BS was studied by using photocatalytic reactor of 3D-Nickel-Net coated with nano-TiO2 under different experimental conditions，such as initial reactive red dye concentration，pH value，amount of added H2O2。 Results indicated that the combined mode of UV/Nickel-Net/TiO2 showed the highest degradation efficiency for the reactive red dye and 99.8% of decolorization was achieved after 390mins treatment. With the increase in initial dye concentration，the percentage of decolorization was declined obviously. Decolorization percentage higher than 98% after 390 min treatment could be achieved when the initial dye concentration was 20 mg/L. The degradation was found at pH 7，the decolorization was as high as 99.2%. The degradation process could be further promoted by the addition of H2O2. The decolorization could be reached up to 99.4% after 150 min’s treatment with the addition of 1 g/L H2O2.