Abstract: Organic extraction of P2O5 from the dissolution of phosphorite tailings with a mixture of sulfuric acid and hydrochloric acid was investigated with effects of extraction and back extraction conditions. The dissolution was purified firstly by evaporation to remove impurities. P2O5 extraction rate of higher than 68% could be achieved under the optimum conditions using n-butyl alcohol as extractant under ambient temperature for 10min from sample with P2O5 concentration of 48% and the phase ratio of 3∶1. The back extraction rate of P2O5 from organic phase could be achieved to higher than 90% using water as the back extractant with water dosage of 30% of the organic phase volume under ambient temperature for 5min. Concentration of the obtained H3PO4 product was as high as 50.49% with very low content of other impurities.