Abstract: The research progress of cyclopentanone synthesis is summarized，including pyrolysis of adipic acid and its derivatives，N2O direct oxidation without catalyst at high temperature and pressure，cyclopentene hydration with subsequent dehydrogenation，oxidation of cyclopentene catalyzed by Waker-type catalyst and so on. Emphasis is given to the reaction mechanisms and catalytic activities of the catalysts. Through the discussion of the advantages and disadvantages of these methods，their industrial application is prospected.