Abstract: The serious problems and necessities of sustainable development in China are described. The definitions of sustainability and process system engineering (PSE) are then discussed. In the major part of this paper，two aspects of PSE to meet sustainability are focused on: the first is inner-enterprise process integration including its methods and applications，the advanced PSE method was put forward in special; the other is inter-enterprise process integration including two integration models and some typical integration methods. Through this process systems engineering review，process integration is recommended to meet the challenges to sustainability. More than 70 key references are attached.