Abstract: N-Nitrosodimethylamine (NDMA) is a potent carcinogen present in food，consumer goods and contaminated air，and its toxicity has been investigated. NDMA，the newborn DBPs，is bound to become the research focus in water environment. The formation mechanism of NDMA was introduced，and the sample pretreatment of NDMA including liquid-liquid extraction（LLE），solid phase extraction（SPE）and solid phase micro-extraction was presented. The analytical methods were also summarized，such as gas phase chromatography，GC/MS，GC/MS/MS，high performance liquid chromatography and LC/MS/MS. At last，The prospective research trends were also discussed．