Abstract: Basing on the practical experience and processing principle, the optimization of producing process, in which the butyl alcohol is abstracted from the water phase by the azeotropic distillation of the partly and mutually dissolved, is studied in this paper by utilizing the properties of the azeotropic distillation of the partly and mutually dissolved system of butyl alcohol and water, from the some questions such as rearranging of the equipments, dissolving with sodium hydroxide, treating of the wasted water, separating water and so on. By comparing the original process with the optimal result，it is shown that the benefits in energy saving and economy were improved greatly and the optimization technology will be good example for the process of butyl alcohol extraction by azeotropic distillation.