Abstract: Due to a series of food safety incidents，food safety has obtained more attention in our country. The detection of pathogenic microorganisms in food using immunomagnetic microsphere(IMMS) is more convenient and faster than conventional detection methods. The application principle and preparation methods of IMMS are reviewed. The application of IMMS for microorganism detection in food is further presented，and at the same time，the application of IMMS in conjunction with other detection methods such as PCR，ELISA，FIA and ECL applied in rapid pathogens detection is also introduced. This approach will become a trend in the development for food microorganism detection.

摘要： 由于一系列食品安全事件的发生，食品安全在我国进一步受到重视，应用免疫磁性微球检测食品中的致病微生物比常规检测方法更加方便、快捷。本文介绍了免疫磁性微球的应用原理和微球的制备方法，并进一步阐述了免疫磁性微球在食品微生物检测中的应用，以及食品致病菌的快速检测中免疫磁性微球与PCR、ELISA、FIA、ECL等检测手段的联用，表明该方法将成为食品微生物检测的一个发展趋势。