Abstract: Mesoporous，organic-inorganic hybrid SBA-15-SO3H containing alkyl(methyl) and sulfonic acid groups was directly synthesized. The catalyst was effective in the synthesis of 2-t-butyl-p-cresol by the alkylation of MTBE with p-creso. Moreover，the influence of alkylation reaction condition on the conversion and selectivity of alkylation and the stability of catalyst was investigated. The experimental result showed that the conversion rate of p-cresol was 87.4%，the selectivity rate was 97.86%，SBA-15-SO3H molecular sieve was an ideal catalyst for the synthesis of 2-t-butyl-p-cresol.

摘要： 以磺酸基介孔分子筛SBA-15-SO3H为催化剂，甲基叔丁基醚（MTBE）和对甲酚为原料合成了2-叔丁基对甲酚。考察了烷基化反应条件对反应转化率和选择性的影响以及催化剂的稳定性。结果表明，对甲酚转化率为87.4%，选择性为97.86%，SBA-15-SO3H分子筛是合成2-叔丁基对甲酚的理想催化剂。