Abstract: Continuous distillation processes including three-tower，four-tower and five-tower for separation of methyl cyanoacetate were proposed to replace the conventional batch distillation process. The best separation technology，that is five-tower continuous distillation，was determined based on the process technological analysis. Optimization simulations of five-tower continuous distillation were performed with ASPEN PLUS software in which RADFRAC model and WILSON equation were used，and the optimum operating conditions and equipment parameters were determined. The industrial data showed that the five-tower continuous distillation can reduce energy consumption by 30%，increase product’ yield by 2.4% compared with the batch distillation. A new process scheme for continuous separation of methyl cyanoacetate was established.

摘要：

针对氰乙酸甲酯传统的间歇精馏分离过程，提出了连续精馏分离氰乙酸甲酯的三塔、四塔和五塔工艺流程，并对3种分离流程进行工艺分析，确定了连续精馏五塔分离工艺。利用ASPEN PLUS软件中的RADFRAC精馏模型和WILSON方程对五塔精馏分离流程进行优化模拟计算，得到了该流程的最佳工艺操作参数及相关的设备参数。生产数据表明，与目前普遍采用的间歇精馏工艺相比，能耗降低了近30％，产品收率提高了2.4％，为氰乙酸甲酯的连续分离开辟了一条新的工艺技术路线。