Abstract: The penetration coefficient of Na+ in copolymer hydrogel membrane of γ- (methacryloyl - oxy) propyltrimethoxysilane (KH 570)，hydroxyethylmethacrylate（HEMA） and N-vinylpyrrolidone (NVP) was measured, and the factors influencing the penetration coefficient of Na+ were investigated as well. The results showed that the diffusion process of Na+ in the hydrogel was stable diffusion, and the penetration coefficient increased remarkably when the temperature increased, while the increase in penetration coefficient dropped when the temperature was over 60℃. The penetration coefficient increased as the content of KH 570 or NVP increased, while the penetration coefficient decreased as the content of KH 570 was over 15wt%. The reason was Na+ being captured by the microholes of the hydrogel.

摘要： 采用腔膜法测定Na+在γ-（甲基丙烯酰氧）丙基三甲氧基硅烷（KH570）与甲基丙烯酸羟乙酯（HEMA）及N-乙烯基吡咯烷酮（NVP）共聚物水凝胶角膜接触镜材料中的渗透系数，研究了Na+渗透系数的影响因素。结果表明，Na+在水凝胶膜中的扩散过程为稳态扩散，其渗透系数随温度升高而显著增大，但温度超过60℃，Na+渗透系数的增大幅度显著下降；水凝胶膜中Na+的渗透系数随NVP及KH570质量分数增多而增大，但KH570的质量分数超过15%，Na+的渗透系数反而随KH570含量增多而减小，其原因在于Na＋被聚合物中的微孔陷阱捕获而无法跳出。