Abstract: Fine ginger oil was extracted with supercritical carbon dioxide （SC-CO2）. A procedure of rapid pressure reduction was designed in order to break the cell wall and reduce the resistance of mass transfer. Using the method of orthogonal design L18（37），the optimum parameters were obtained under the fragmentation pressure of 20.0 MPa，isobaric time of 30min，pressure reduction of 10 MPa/min，extraction pressure of 16.0MPa，extraction temperature of 45.0℃ and extraction time of 60min when the flux of CO2 was 20 m3/h. Compared with the method of Soxlet extraction，this method achieved a higher yield （about 3.62%），Compared with SC-CO2 extraction，the extractipn pressure，temperature and time were reduced obviously in this process，and the yield increased by 1.32 times. Base on these parameters，a pilot scale equipment was designed and fine ginger oil could be extracted with SC-CO2 by running over 4000 hours.

摘要： 采用超临界CO2萃取生姜精油，设计了一个突然降压的过程，使生姜块茎的细胞壁破碎，减少过程的传质阻力。通过L18（37）正交试验得出其最优的工艺条件为：破碎压力20.0 MPa，恒压时间30 min，降压速率为10.0 MPa/min，萃取压力16.0 MPa，萃取温度45 ℃。在CO2流量为20.0 m3/h时，萃取60 min可完成操作。与索氏（溶剂）提取法相比，其收率很高（约3.62%）；与超临界CO2萃取法相比，该方法的萃取温度、萃取压力和操作时间有较大降低，产品收率提高1.32倍；据此设计的150 L中试装置，经过4000 h的试运行证明，该装置用于萃取姜油可完全满足工艺要求。