Abstract: The alkene ozonolysis reaction is introduced，and the reactions of the produced zwitterion with alcohols，amine oxides，water and Lewis acids as well as the zwitterion isomerization are discussed. Applications of the corresponding products from these reactions of zwitterion in chemical industry，pharmaceuticals and fragrant compounds are summarized. The development in the research of zwitterion reactions in recent ten years is introduced in detail.

摘要： 介绍了烯烃臭氧化反应，论述了臭氧化反应中生成的两性离子与醇、氧化胺、水、路易斯酸的反应以及两性离子的异构化反应及其在合成相关化工、医药、香料产物方面的应用，并对近十年来两性离子反应的研究进展进行了综述。