Abstract: This paper introduces the advancement in research on replacement of CH4 from hydrate with CO2，and discusses the thermodynamic feasibility of replacment reaction between CO2 and CH4 hydrate，and points out that correct understanding of the replacement mechanism，new reaction techniques and higher reaction rate will be the key to commercial application.

摘要： 介绍了近年来CO2置换开采天然气水合物技术的研究进展；论述了CO2与天然气水合物中CH4置换反应在热力学上的可能性；认为正确理解置换反应机理、探索新的反应技术并提高反应速率是置换开采技术走向产业化的关键。